Cerebral Folate Deficiency

Folate Antibodies Across Generations - A Research Update from Dr. Richard Frye

Dr. Richard E. Frye walks through new research on folate receptor alpha autoantibodies and how they appear to build from one generation to the next. Paper: Frye et al., "Transgenerational Effects and Heritability of Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorder," IJMS 2025.

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Folate and the Microbiome - A Research Update from Dr. Richard Frye

Dr. Richard E. Frye walks through a new systematic review of how gut bacteria make and consume folate, and what happens to health when that balance breaks down. Paper: Khanduja & Frye, "A Systematic Review of Folate and the Human Enteric Microbiome," IJMS 2026.

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Is a Folate Deficiency Worsening Your Child’s Autism?

Posted by: Potomac Psychiatry
Posted on:  April 13, 2023

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Cerebral Folate Deficiency in Autism Spectrum Disorders

Frye, RE, Rossignol D. Autism Science Digest: The Journal of Autismone. Issue 2. pp. 9-15.

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Central Folate Abnormalities

Frye, RE. Autism File: Autism & Treatments. 2017. pp. 25-29.

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