A Mitochondrial Supplement Trial in Autism - A Research Update from Dr. Richard Frye
Dr. Richard E. Frye walks through a double-blind, placebo-controlled crossover trial of a mitochondrial supplement in children with autism. Paper: Hill et al., "A Mitochondrial Supplement Improves Function and Mitochondrial Activity in Autism," IJMS 2025.
How Gut Bacteria Talk to Mitochondria - A Research Update from Dr. Richard Frye
Dr. Richard E. Frye walks through a new review of how gut bacteria affect mitochondria, the structures that make energy inside nearly every cell. Paper: Frye & Rossignol, "Mechanistic Pathways Linking Gut Microbial Metabolites, Microbial Structural Products, and Host-Microbe Co-Metabolites to Mitochondrial Function," Gut Microbes 2026.
Mitochondrial Dysfunction in Autism Spectrum Disorder
Frye, RE. The Autism File: Biomedical Update. 2015. pp. 28-34.
Mitochondrial Dysfunction and Autism Spectrum Disorders: A Simplified Approach
Rossignol, DA, Frye, RE. Autism Science Digest: The Journal of Autismone. 2011. pp. 21-27.

